Unilateral Carotid Body Resection in Resistant Hypertension
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چکیده
منابع مشابه
Unilateral Carotid Body Resection in€Resistant Hypertension
SEE PAGE 313 H ypertension is a highly prevalent condition and, when untreated, has myriad devastating consequences including myocardial infarction, cardiomyopathy, renal failure, and stroke. Extensive clinical data support the treatment of hypertension and demonstrates the reduction in cardiovascular events, stroke, and death in patients with hypertension whose blood pressure is controlled (1)...
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Krzysztof Narkiewicz, MD, Laura E.K. Ratcliffe, BSC, MBBS, Emma C. Hart, PHD, Linford J.B. Briant, PHD, Marzena Chrostowska, PHD, Jacek Wolf, MD, Anna Szyndler, MD, Dagmara Hering, MD, Ana P. Abdala, PHD, Nathan Manghat, MD, Amy E. Burchell, MA, BMBCH, Claire Durant, PHD, Melvin D. Lobo, Paul A. Sobotka, MD, Nikunj K. Patel, MBBS, MD, James C. Leiter, MD, Zoar J. Engelman, PHD, Angus K. Nightin...
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Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure in conditions of hypertension. This first-in-man, proof-of-principle study tested the safety and feasibility of unilateral carotid body resection in 15 patients with drug-resistant hypertension. The procedure proved to be safe and feasi...
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Bilateral bipolar electric carotid sinus stimulation acutely reduced muscle sympathetic nerve activity (MSNA) and blood pressure (BP) in patients with resistant arterial hypertension but is no longer available. The second-generation device uses a smaller unilateral unipolar disk electrode to reduce invasiveness while saving battery life. We hypothesized that the second-generation device acutely...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2016
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2016.07.001